According to MedlinePlus, the probiotic supplements lactobacillus and bifidobacteria are likely safe when used as directed. Potential side effects can include intestinal upset, bloating or gas. Pregnant or breast-feeding women and those with weakened immune systems should avoid probiotics. If using probiotics concomitantly with antibiotics, be A urinary tract infection (UTI) is an infection in any part of the urinary system. The urinary system includes the kidneys, ureters, bladder and urethra. Most infections involve the lower urinary tract — the bladder and the urethra. Women are at greater risk of developing a UTI than are men. If an infection is limited to the bladder, it can The Lactobacillus strain GR-1 can generate oxidative stress responses that inhibit Candida albicans, prevent its biofilm formation, and depending on the conditions, can actually kill the fungus . The ability to stress the outer membrane of E coli has also recently been discovered in our study group, in part due to its lactic acid and hydrogen However, unlike the known effects of adherent Lactobacillus species in inhibiting extracellular E. coli and other prospective pathogens from colonizing the vaginal epithelial surface, the inhibitory effect in the bladder seemed to be targeted at UPEC harbored within BECs. Small intestinal bacterial overgrowth (SIBO) is the presence of excess colonic bacteria in the small intestine. These excess organisms result in multiple intestinal symptoms like abdominal pain, bloating, diarrhea, and rarely malabsorption. [1]. The proximal small intestine typically contains relatively few bacteria due to the presence of stomach acid and the effects of peristalsis Abstract. Escherichia coli is one of the species most frequently involved in biofilm-related diseases, being especially important in urinary tract infections, causing relapses or chronic infections. Compared to their planktonic analogues, biofilms confer to the bacteria the capacity to be up to 1000-fold more resistant to antibiotics and to BP5bWE. Lactobacilli are among the most studied bacteria in the microbiome of the orodigestive and genitourinary tracts. As probiotics, lactobacilli may provide various benefits to the host. These benefits include regulating the composition of the resident microbiota, preventing – or even potentially reverting- a dysbiotic state. Candida albicans is an opportunistic pathogen that can influence and Escherichia coli (E. coli) is a bacterium that normally lives in the intestines of people and animals.Certain types can cause an intestinal infection. It can lead to severe, potentially life But of the mice that had both species, 6 percent showed severe kidney damage, high levels of E. coli in the kidney and signs that E. coli had moved from the kidney to the bloodstream, a form of UTI that can kill. In other words, the presence of G. vaginalis made E. coli more likely to cause severe kidney disease. In the absence of Lactobacillus strains, only 2% of adherent E. coli UTI89 were invasive while 17% of adherent E. coli CFT073 were invasive (100% = 1 × 10 8 cfu mL −1). While there was a general trend for reduction of invasiveness for both UTI 89 and CFT073 coinoculated with Lactobacillus spp., results did not reach significance. In the study by Shokryazdan and colleagues the intermediate antagonistic effect of several lactic acid bacteria, including different strains of Lactobacillus casei, Lactobacillus acidophilus, Lactobacillus fermentum against different pathogens including E. coli ATCC 29181 an inhibition zone between 11.3 and 14.4 mm. Kholy and colleagues also Strains of Lactobacillus casei isolated from Iranian traditional yoghurts showed potential activity against enteropathogenic E. coli and Salmonella spp. . Djadouni and Kihal [ 19 ] screened LAB from dairy, meat products and agro-industrial wastes and isolated a LAB strain (LBbb0141) that contained antimicrobial compound with a wide spectrum and

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